An assassination Rogue is one of the more popular Raiding specs out there. This Raiding spec build guide will cover the best dps talents for your 85 rogue along with some recommended glyphs. This guide is updated for Cataclysm patch 4.0.3 and patch 4.0.6.
Remember, there is no perfect build or glyph set. The perfect build or glyphs depends on who is in your raid and your own play-style. The glyphs are recommendations, and the minor glyphs are definately up to you as they dont change your dps whatsoever.
These are the best 1-85 raiding leveling points to go along with the best 1-85 leveling route: Zygor’s Leveling Guide
Level 85 Rogue (31/3/7) (Link)
Assassination (31 Points)
Coup de Grace – Rank 3/3
Increases the damage done by your Eviscerate and Envenom abilities by 20%.Lethality – Rank 3/3
Increases the critical strike damage bonus of your Sinister Strike, Backstab, Mutilate and Hemorrhage abilities by 30%.Ruthlessness – Rank 3/3
Gives your melee finishing moves a 60% chance to add a combo point to your target.Quickening – Rank 2/2
All healing effects on you are increased by 20% and your movement speed is increased by 15%. This does not stack with other movement speed increasing effects.Puncturing Wounds – Rank 3/3
Increases the critical strike chance of your Backstab ability by 30%, and the critical strike chance of your Mutilate ability by 15%.Deadly Brew – Rank 1/2
When you apply Instant, Wound or Mind-Numbing Poison to a target, you have a 50% chance to apply Crippling Poison.Cold Blood – Rank 1/1
When activated, generates 25 Energy and increases the critical strike chance of your next non-periodic offensive ability by 100%.Vile Poisons – Rank 3/3
Increases the damage dealt by your poisons by 20% and gives you 100% of the normal chance of applying poisons from your equipped melee weapons when you use the Fan of Knives ability.Seal Fate – Rank 2/2
Your critical strikes from abilities that add combo points have a 100% chance to add an additional combo point.Murderous Intent – Rank 2/2
When you Backstab an enemy that is below 35% health, you instantly recover 30 Energy.Overkill – Rank 1/1
While stealthed, and for 20 seconds after breaking stealth, you regenerate 30% additional energy.Master Poisoner – Rank 1/1
Increases the spell damage taken by any target you have poisoned by 8%, causes your Envenom ability to no longer consume Deadly Poison, and reduces the duration of all Poison effects applied to you by 50%.Cut to the Chase – Rank 3/3
Your Eviscerate and Envenom abilities have a 100% chance to refresh your Slice and Dice duration to its 5 combo point maximum.Venomous Wounds – Rank 2/2
Each time your Rupture or Garrote deals damage to an enemy that you have poisoned, you have a 60% chance to deal 675 additional Nature damage and to regain 10 Energy. If an enemy dies while afflicted by your Rupture, you regain energy proportional to the remaining Rupture duration.Vendetta – Rank 1/1
Marks an enemy for death, increasing all damage you deal to the target by 20% and granting you unerring vision of your target, regardless of concealments such as stealth and invisibility. Lasts 30 sec.
Combat (3 Points)
Precision – Rank 3/3
Increases your chance to hit with weapon and poison attacks by 6%.
Subtlety (7 Points)
Nightstalker – Rank 2/2
Increases your speed while stealthed by 15% and reduces the cooldown of your Stealth ability by 6 sec.Relentless Strikes – Rank 3/3
Your finishing moves have a 20% chance per combo point to restore 25 energy.Opportunity – Rank 2/3
Increases the damage dealt with your Backstab, Mutilate, Garrote and Ambush abilities by 20%.
Glyphs
Glyph of Mutilate (Prime Glyph)
Reduces the cost of Mutilate by 5 energy.Glyph of Rupture (Prime Glyph)
Increases the duration of Rupture by 4 sec.Glyph of Backstab (Prime Glyph)
Your Backstab critical strikes grant you 5 energy.Glyph of Tricks of the Trade (Major Glyph)
Removes the energy cost of your Tricks of the Trade ability but reduces the recipient’s damage bonus by 5%.Glyph of Feint (Major Glyph)
Reduces the energy cost of Feint by 20.Glyph of Sprint (Major Glyph)
Increases the movement speed of your Sprint ability by an additional 30%.Glyph of Blurred Speed (Minor Glyph)
Enables you to walk on water while your Sprint ability is active.Glyph of Safe Fall (Minor Glyph)
Increases the distance your Safe Fall ability allows you to fall without taking damage.Glyph of Distract (Minor Glyph)
Increases the range of your Distract ability by 5 yards.
Do You Want To Level Faster Like The Pros?
If you are having trouble leveling or need to level faster in WoW Cataclysm I highly suggest you check out Zygor’s Leveling Guide. It has the perfect leveling path that gets you to 85 faster and easier than any other way. No matter what level you are, you load the guide and it points with an arrow to the direction of each monster, quest giver, trainer etc. Its pretty crazy. It also has an in game box that tells you exactly what to do, like kill 5 boars, run west 10 miles, etc. If you dont have this in game add on guide, honestly, you are missing out. You can find out more here or check out the Zygor Cataclysm Leveling Guide Review.

You should change Precision – Rank to 2/3 and place that extra talent point in Opportunity – Rank 3/3
(Increases the damage dealt with your Backstab, Mutilate, Garrote and Ambush abilities by 30%).
Getting hit capped is still doable and pretty easy with reforging without loosing dps and with 30% dmg dealth with mutilate, backstab and garrote you will love your dps on boss encounters.
Sure if you just turned 85 then Precision rank 3/3 would help a lot but when you get better gear you will see getting hit capped gets easier so changing to
Precision 2/3 and placing that extra point in Opportunity would be best!
Except assassination is all poison damage. the extra 2% to hit increases damage done by a significant margin.